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Liver Pathology P’s and Q’s: The Perplexing and the Quotidian

Original release date:
March 14, 2022
Access to this course expires on:  January 24, 2025 at 11:59 PM Pacific Time
CME 10.75

Course Description
This comprehensive approach to pathology of the liver, gallbladder and biliary tree is designed for junior and experienced pathologists who encounter these specimens in daily practice. Medical advances in management of patients with liver disease have dramatically changed the histologic patterns encountered in liver biopsies which are increasingly obtained from patients with multiple medical problems who take multiple medications. Classification of tumors of the liver, biliary tree and gallbladder has also become increasingly complex.

This course is intended to provide clarity on the common and uncommon patterns of injury seen in liver biopsies. Usual and unusual causes of acute hepatitis, chronic hepatitis and cholestatic liver disease will be discussed. Tools to solve challenging metabolic and pediatric liver disease will be provided. Guidance will be given on how to interpret liver biopsies from patients with complex systemic diseases. A substantial portion of the course will address how to approach tumors involving the liver, biliary tree and gallbladder. Correct classification requires recognition of specific morphologic features, judicious use of immunohistochemistry and selective application of molecular diagnostics.

Target Audience
Practicing academic and community pathologists, and pathologists-in-training

Learning Objectives
Upon completion of this educational activity, learners will be able to:
  • Recognize the common and uncommon causes of acute hepatitis, chronic hepatitis and cholestatic liver disease
  • Correctly classify usual and unusual tumors of the liver, biliary tree and gallbladder
  • Understand the important metabolic diseases that affect the liver
  • Identify patterns of injury that commonly affect pediatric patients
  • Distinguish systemic diseases affecting the liver from primary liver diseases

Continuing Medical Education
The United States and Canadian Academy of Pathology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The United States and Canadian Academy of Pathology designates this enduring material for a maximum of 10.75 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The faculty, committee members, and staff who are in position to control the content of this activity are required to disclose to USCAP and to learners any financial relationship(s) that have occurred within the last 24 months with any commercial interest(s) whose products or services are related to the CME content. USCAP has reviewed all disclosures and mitigated all identified conflicts of interest, as applicable.

The following faculty reported no relevant financial relationships: Maha Guindi, MD, FRCPC, John A. Hart, MD, Maria Westerhoff, MD

The following faculty reported relevant financial relationships: Rish K. Pai, MD, PhD: Consultant, Alimentiv, Allergan, Eli Lilly

The following IM Coordinator reported no relevant financial relationships: Scott Owens, MD

USCAP staff associated with the development of content for this activity reported no relevant financial relationships.

To earn CME credit, all learners must complete the evaluation. View and print your certificate by clicking here.

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