Original release date: December 19, 2022
Access to this course expires on:  October 25, 2025 at 11:59 PM Pacific Time
CME 12.25

Course Description
Based on multi-institutional practices handling large volumes of breast pathology cases at established cancer centers and cumulative consultation cases, this expert faculty has identified areas that pose diagnostic and interpretative challenges in recurrent problematic areas deserving attention: intraductal epithelial proliferations and microinvasive carcinoma, lobular neoplasia including LCIS variants, papillary lesions, and benign vs malignant spindle cell lesions. The interpretation of immunohistochemical stains (IHC) with focus on predictive markers can also be challenging. This interactive microscopy course is designed to illustrate distinct challenging entities and problematic issues, with practical approaches to their resolution in real time, in the context of intimate mentoring.

Target Audience

Practicing academic and community pathologists, and pathologists-in-training

Learning Objectives

Upon completion of this educational activity, learners will be able to:

• Develop a practical approach for the diagnostic evaluation of intraductal epithelial proliferations (UDH, FEA, ADH, DCIS)
• Refine the diagnosis of LCIS (including WHO 2019 criteria for Pleomorphic and Florid LCIS) and invasive lobular carcinomas, with interpretation of related IHC.
• Develop a practical approach for the diagnosis of papillary lesions, including variants of papillary carcinoma, with review of ancillary IHC and management at core biopsy
• Cultivate a practical approach for the diagnosis of fibroepithelial neoplasms and special subtypes of breast carcinomas, including needle biopsy diagnoses and patient management
• Learn about the applications of diagnostic, prognostic and predictive IHC markers in breast pathology, with emphasis on the interpretation, reporting an possible pitfalls

Continuing Medical Education

The United States and Canadian Academy of Pathology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The United States and Canadian Academy of Pathology designates this enduring material for a maximum of 12.25 AMA PRA Category 1 Credits^TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosures

The faculty, committee members, and staff who are in position to control the content of this activity are required to disclose to USCAP and to learners any financial relationship(s) that have occurred within the last 24 months with any commercial interest(s) whose products or services are related to the CME content. USCAP has reviewed all disclosures and mitigated all identified conflicts of interest, as applicable.

The following faculty reported no relevant financial relationships: Edi Brogi, MD, PhD, Kimberly Heller Allison, MD, Melissa P. Murray, DO, Melinda Ellen Sanders, MD

The following IM Coordinator reported no relevant financial relationships: Laura C. Collins, MD

USCAP staff associated with the development of content for this activity reported no relevant financial relationships.

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